This question was answered on Fri 13, Jan 2012 01:35pm by Dr Sheetal Kaul

hypothyroidism

    
Asked by tiger lilly (Female; 51; tonsils and adenoids removed in childhood to cure deefness ) on Fri 13, Jan 2012 09:21am
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Dear Doctor I am writing this letter because I find it difficult to talk about my symptoms. If you ask how I feel, I usually respond with alright, but the truth is I feel far from it. The days when I wake up and feel anything like normal are few and far between. My symptoms consist of: • Tiredness and lethargy. • Intolerance to cold (I have always been this way. As a teenager, I was the only one of my peers to take their coat on a night out. I always take a jacket out with me for summer evenings for fear of getting cold. When I get cold I am completely miserably and very short tempered. My siblings, partner and children have often been at the receiving end of this and just dismiss it as they know I am cold. My feet and sometimes legs go blue and the pain in my hands and feet is extreme whilst the rest of me just hurt. I avoid going out in the winter and only venture out in the cold when absolutely necessary. As I am not employed I very rarely venture out of the house). • Dry skin and hair loss (my body hair is plentiful but the hair on my head falls out in hands full). • Poor memory and difficulty concentrating (some days I am fine, I use these days to cram in as much as I can, other days I struggle) • Constipation (I have an intolerance to puff wheat so I use them and bran flakes to try and combat this) • Decreased appetite and weight gain. I very rarely feel hungry and often just have a meal in the evening with my partner. I don’t snack and chocolate and biscuits are a treat that I go months without). I have not had a weight issue in the past; however, just recently, my weight has rapidly increased, despite exercise. • I think my general hearing is ok, but I have a problem when people whisper. Loud noise makes my head feel like it is about to explode. My ears often feel like they need to pop and I sometimes get whooshing noises. • Reduced libido. I don’t think I have any, thankfully I have an understanding Partner, although I do believe it is a problem for him. • Cold peripheries. I have always had cold hands and feet. My feet are nearly always blue. My big toe turns black just above the toe nail. Putting on a pair of socks usually returns them to a normal colour, but I am then limited to wearing trainers during summer months as people often comment on my blue feet if I wear open toe shoes or sandals. When my hands get cold my fingers will sometimes go white and go numb, but retain their movement, although it is with some difficulty. • I often wake up with a puffy face; it does not look like me in the mirror. This soon reduces and goes back to normal usually within an hour. I have a son who has been diagnosed with goitre and consequently had a TSH test. I had a raised TSH result, but the follow on T3/T4 result was normal. The doctor I consulted told me that the results were fine and I must have been ill when the first test was taken. However, further reading suggests that I may have hypothyroidism. I realise that this letter sound like a big moan, but I generally feel like crap. Today I cannot stop crying. I have no major problems in my life and I am excitedly looking forward to my wedding next month, in Cuba. But still today is a cry day, I feel like crap and cannot stop crying. When I wake up tomorrow I will probably be ok. I will still feel like crap, but without the crying. I have low self-esteem and if I was to self-diagnose myself, I would say I have acute hypochondria. If this is the case I would like treatment for it. Am I just depessed?

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Answer by Dr Sheetal Kaul  on Fri 13, Jan 2012 01:35pm:

Hi there! Welcome to the forum. I understand what you have been going through and how you must be feeling. Well, most of the symptoms mentioned by you such as intolerance to cold, depression, dry skin, loss of hair, loss of appetite, weight gain, irregular menstruation, reduced libido, reduced concentration, constipation etc. and are commonly associated with long standing low thyroid levels. In the presence of high TSH and normal T3/T4, I would suggest a repeat thyroid profile and if still the T3/T4 happen to within the normal range it might still be a good idea to maintain T3/T4 on the higher side of the normal range for symptomatic control. I would also suggest getting a complete hormonal/ endocrine profile and blood sugar levels tested for along with tests for autoimmune conditions. These have often been found to be associated and could present similarly. If still all results happen to be within the normal range, you may be started on generic medications that help in individual control of symptoms. I would suggest a detailed evaluation by an internist or an endocrinologist for the same. Hopefully things would get better with appropriate management. Hope this is helpful. Please feel free to post any further queries that you may have and do keep us posted. Take care and Best wishes for a Happy Married Life!

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Comment by Dr.Kokil Mathur on Fri 13, Jan 2012 06:44pm:
Hi! I agree with Dr Kaul that most of your symptoms do sound like hypothyroidism. A high TSH with normal blood thyroid hormones (T3 and T4) means a subclinical hypothyroidism. In such a setting, Hashimotos’s thyroiditis should be tested for which is an autoimmune disorder. However in 10-15% cases of Hashimotos the test comes back normal. Hence other thyroid antibodies such as antithyroglobulin (anti-Tg), and to a lesser extent, TSH receptor-blocking antibodies, thyroid-stimulating antibody and cytotoxic antibody should be tested for. Also the tests should be repeated after 3 months. Since you also feel hungry chances of diabetes, and polycystic ovary (PCOD) affecting the glucose metabolism is very high. Hence an abdominal ultrasound should be done to rule out PCOD. Blood sugar fasting, two hours after meal, and glycosylated hemoglogin or HbAc1 should be done. Vit B12 deficiency causes feeling cold, tiredness, dizziness etc. Low intrinsic factor in gut that hampers absorption of B12 and causes pernicious anemia is the commonest cause. If this is so the increasing intake of B12 will not help, and you will need to take Vitamin B12 injections at regular frequency as prescribed by your doctor. Other causes are parasites in the gut, diet poor in Vit B12, Crohn's disease, IBS, or poor metabolism by liver are the causes behind it. Please consult a doctor to rule these out. Take a diet rich in Vit B12 which should include meat and animal products, cheese, such as beef, liver, salmon, cod, and eggs. Take B12 supplements and breakfast cereals fortified with vitamin B12. Finding the cause is important. Addison’s disease, adrenal causes like pheochromocytoma, anemia, Buerger’s disease, chronic fatigue syndrome and Raynaud’s disease are the other causes which need to be ruled out. You will need some tests like blood tests, treadmill test, color Doppler, angiography, ultrasonography and MRI (magnetic resonance imaging). You need to consult a good endocrine specialist. It is difficult to comment beyond this at this stage. Hope this gives you an idea as to what needs to be done. Please let me know if there is any thing else and do keep me posted. Take care!

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